Physiological Pharmacokinetics

[+] Author and Article Information
R. L. Dedrick

National Institutes of Health Public Health Service, Department of Health, Education, and Welfare, Bethesda, Md. 20014

J. Dyn. Sys., Meas., Control 95(3), 255-258 (Sep 01, 1973) (4 pages) doi:10.1115/1.3426711 History: Received May 14, 1973; Online July 13, 2010


This paper reviews the physiological bases of pharmacokinetics and discusses the use of physiological and biochemical information in developing compartmental models. Pharmacokinetic principles are illustrated by reference to published work on methotrexate distribution in several animal species. Use of pharmacokinetics in predicting drug effect is cited.

Copyright © 1973 by ASME
Your Session has timed out. Please sign back in to continue.





Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related Journal Articles
Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In