Instability and Mitotic Patterns in Tissue Growth

[+] Author and Article Information
Leon Glass

Institute for Fundamental Studies, Department of Physics and Astronomy, The University of Rochester, Rochester, N. Y.

J. Dyn. Sys., Meas., Control 95(3), 324-327 (Sep 01, 1973) (4 pages) doi:10.1115/1.3426723 History: Received May 16, 1973; Revised June 29, 1973; Online July 13, 2010


A mathematical model which reproduces several qualitative features of cancerous tumor growth is proposed. The onset of unstable growth is characterized by a dimensionless number, which is defined in terms of the parameters describing the system. Patterns of mitotic activity of the model system are compared with experimentally observed patterns of mitotic activity in cancerous tissues.

Copyright © 1973 by ASME
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