Review Article

Terminal Synergetic Control for Blood Glucose Regulation in Diabetes Patients

[+] Author and Article Information
A. Hachana

QUERE Laboratory,
Electrical Engineering Department,
Ferhat Abbas University of Setif1,
Sétif 19000, Algeria
e-mail: hachana.ai@yahoo.fr

M. N. Harmas

QUERE Laboratory,
Electrical Engineering Department,
Ferhat Abbas University of Setif1,
Sétif 19000, Algeria
e-mail: mharmas@yahoo.fr

Contributed by the Dynamic Systems Division of ASME for publication in the JOURNAL OF DYNAMIC SYSTEMS, MEASUREMENT,AND CONTROL. Manuscript received May 20, 2017; final manuscript received March 15, 2018; published online May 3, 2018. Assoc. Editor: Sergey Nersesov.

J. Dyn. Sys., Meas., Control 140(10), 100801 (May 03, 2018) (5 pages) Paper No: DS-17-1260; doi: 10.1115/1.4039716 History: Received May 20, 2017; Revised March 15, 2018

In this paper, a new robust terminal synergetic control scheme is proposed to regulate blood glucose level in diabetic patients (type I diabetes), based on recently developed synergetic control and a terminal attractor technique. The technique presented has the advantage of using a continuous control law. Moreover, the proposed control scheme, besides being chattering free, has the characteristics of finite time convergence. Lyapunov synthesis is adopted to ensure controlled system stability. Simulation results of terminal synergetic control are compared to classic synergetic and second-order sliding mode control (SMC) performance, demonstrating that the proposed control method allows for rapidly achieving normoglycemia in type I diabetes patients.

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Grahic Jump Location
Fig. 1

Glucose concentration using synergetic control

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Fig. 2

Glucose concentration using terminal synergetic control

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Fig. 3

Insulin concentration using synergetic control

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Fig. 4

Insulin concentration using terminal synergetic control

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Fig. 5

Comparing the three controllers: glucose concentration for (a) patient 1, (b) patient 2, and (c) patient 3, representing a hyperglycemic event

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Fig. 6

Blood glucose response of a day with three meals

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Fig. 7

Insulin infusion response of a day with three meals




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